![]() We show that incubating MA- 10 Leydig cells with mono-(2-ethylhexyl) phthalate (MEHP) resulted in reductions in luteinizing hormone (LH)-stimulated cAMP and progesterone productions. However, the affected components of the steroidogenic pathway, and the mechanisms involved, remain uncertain. Previous studies have shown that phthalate exposure can suppress steroidogenesis. Lin, Chieh-Yin Liu, June Traore, Kassim Papadopoulos, Vassilios Zirkin, Barry R. ![]() Oxidative Stress and Phthalate-Induced Down-Regulation of Steroidogenesis in MA- 10 Leydig Cells*
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